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METHODS AND COMPOSITIONS FOR TREATING UROLOGICAL DISORDERS USING 313, 333, 5464, 18817 OR 33524

机译:使用313、333、5464、18817或33524治疗泌尿系统疾病的方法和成分

摘要

The present invention relates to methods for the diagnosis and treatment of a urological disorder or urological disorders. Specifically, the present invention identifies the differential expression of 313, 333, 5464, 18817 or 33524 genes in tissues relating to urological disorder, relative to their expression in normal, or non-urological disorder disease states, and/or in response to manipulations relevant to a urological disorder. The present invention describes methods for the diagnostic evaluation and prognosis of various urological diseases, and for the identification of subjects exhibiting a predisposition to such conditions. The invention also provides methods for identifying a compound capable of modulating a urological disorder or urological disorders. The present invention also provides methods for the identification and therapeutic use of compounds as treatments of urological disorders.
机译:本发明涉及诊断和治疗一种或多种泌尿系统疾病的方法。具体而言,本发明鉴定了与泌尿系统疾病有关的组织中的313、333、5464、18817或33524基因在正常或非泌尿系统疾病状态下和/或响应相关操作的差异表达。到泌尿科疾病。本发明描述了用于各种泌尿外科疾病的诊断评估和预后,以及用于鉴定表现出对这种疾病易感性的受试者的方法。本发明还提供了鉴定能够调节一种或多种泌尿科疾病的化合物的方法。本发明还提供了鉴定和治疗用作泌尿科疾病的化合物的方法。

著录项

  • 公开/公告号EP1441684A4

    专利类型

  • 公开/公告日2006-08-02

    原文格式PDF

  • 申请/专利权人 MILLENNIUM PHARMACEUTICALS INC.;

    申请/专利号EP20020795603

  • 发明设计人 SILOS-SANTIAGO INMACULADA;

    申请日2002-11-07

  • 分类号C12N15/67;C12N9/64;C12N15/68;

  • 国家 EP

  • 入库时间 2022-08-21 21:30:23

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