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USE OF THE MCM8 GENE FOR THE PREPARATION OF A PHARMACEUTICAL COMPOSITION

机译:MCM8基因在制备药物组合物中的用途

摘要

The present invention relates to the use of the human or animal MCM8 gene coding for a DNA helicase, or parts of said gene, or transcripts thereof, or antisense nucleic acids able to hybridize with part of said transcripts, or silencing RNA derived from parts of said transcripts and able to repress said MCM8 gene, or proteins or peptidic fragments translated from said transcripts, or antibodies directed against said proteins or peptidic fragments for the preparation of a pharmaceutical composition for the treatment of a human or animal pathology linked to a dysfunction of the expression of the MCM8 gene, or of human or animal cancers.
机译:本发明涉及编码DNA解旋酶或所述基因的部分或其转录物,或能与所述转录本的一部分杂交或使源自RNA的一部分的RNA沉默的反义核酸的人或动物MCM8基因的用途。所述转录本并且能够阻遏所述MCM8基因,或从所述转录本翻译的蛋白质或肽片段,或针对所述蛋白质或肽片段的抗体,用于制备用于治疗与人功能障碍相关的人或动物病理学的药物组合物MCM8基因或人类或动物癌症的表达。

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