DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOSCIATED WITH 5-HYDROXYTRYPTAMINE (SEROTONIN) RECEPTOR 2B (5-HTEB)

摘要

The invention provides a human 5-HT2B which is associated with the reproduction diseases, gastro-intestinal and liver diseases, disorders of the peripheral and central nervous system, urology, diseases, hematology diseases, cancer diseases and cardiovascular diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of reproduction diseases, gastro-intestinal and liver diseases, disorders of the peripheral and central nervous system, urology diseases, hematology diseases, cancer diseases and cardiovascular diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of 5-HT2B as well as pharmaceutical compositions comprising such compounds.