首页> 外国专利> FERULA FUKANENSIS EXTRACT, THE PREPERATION METHOD AND THE USE IN PRODUCING MEDICINE THEREOF

FERULA FUKANENSIS EXTRACT, THE PREPERATION METHOD AND THE USE IN PRODUCING MEDICINE THEREOF

机译:阿魏酸提取物,制备方法及其在制备药物中的用途

摘要

The present invention provides Ferula fukanensis extract, the preparation method and the use in producing medicine thereof. The method of extracting the active compounds includes:1) The Ferula fukanensis is extracted with methanol, the extract solution is concentrated under reduced pressure and dried,then extract is obtained; 2) The extract is extracted with chloroform and ethyl acetate,successively; 3) The chloroform fraction is subjected to column chromatography, eluted with the mixed solution of n-hexane and ethyle acetate; 4) The eluent is further seperated and purified by High Performance Liquid Chromatography, 11 active compounds are obtained. The compounds or the salt, enantiomer, racemer, tautomer or physiological derivative thereof which are extracted from Ferula fukanensis, can be used to prepare the medicine which can treat or prevent inflammation or tumor.
机译:本发明提供了福建阿魏草提取物,其制备方法及其在药物生产中的用途。提取活性成分的方法包括:1)用甲醇提取福建阿魏草,减压浓缩提取液,干燥,得到提取物。 2)萃取液依次用氯仿和乙酸乙酯萃取; 3)对氯仿馏分进行柱色谱,用正己烷和乙酸乙酯的混合溶液洗脱; 4)洗脱液通过高效液相色谱进一步分离和纯化,获得11种活性化合物。从福肯草中提取的化合物或其盐,对映异构体,消旋体,互变异构体或生理衍生物可用于制备可治疗或预防炎症或肿瘤的药物。

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