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SELECTION OF HIGHLY EFFICIENT ANTIGEN PRESENTING CELLS FOR REGULATING IMMUNITY AND USES THEREOF

机译:用于调节免疫力的高效抗原提呈细胞的选择及其用途

摘要

The present invention relates, generally, to the fields of immunology and cellular biology. The invention discloses, more particularly, a new strategy of modulation of immune response based on the use of highly efficient non autologous antigen presenting and/or immunostimulatory system such as allogeneic antigen presenting cells. Invention thus relates to methods for preparing or selecting systems having high antigen presentation and/or immunostimulatory capacity for a given subject. The invention also discloses banks usable to select such systems as well as compositions comprising such systems, their preparation and uses.
机译:本发明通常涉及免疫学和细胞生物学领域。更具体地,本发明公开了基于使用高效的非自体抗原呈递和/或免疫刺激系统例如同种异体抗原呈递细胞的免疫应答调节的新策略。因此,本发明涉及针对给定受试者制备或选择具有高抗原呈递和/或免疫刺激能力的系统的方法。本发明还公开了可用于选择此类系统以及包括此类系统的组合物,其制备和用途的库。

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