ANTI-TELOMERASE SIRNA VECTOR FOR GENE THERAPY OF CANCER OR DIFFERENTIATION OF STEM CELLS

摘要

The present invention relates to tumorigenesis and stem cell differentiation and related telomerase gene therapy using an adjustable telomerase inhibiting siRNA expression vector and using this, the enzymatic activity RNAi technology. ; More specifically, the present invention is possible that inhibition of telomerase that its activity reported in more than 90% of tumor and stem cell gene therapy vector on its application method, the plasmid vectors of the invention a variety of tumor therapy and stem cell It may be useful in the differentiation regulation.