Anti-telomerase siRNA vector for gene therapy of cancer or differentiation of stem cells

摘要

The present invention relates to tumorigenesis and stem cell differentiation and adjustable using the telomerase enzyme activity of the RNAi technology in related telomerase inhibiting siRNA expression vectors and gene therapy using the same. ; More specifically, the invention relates to a gene therapy vector and a method of application is possible inhibition of telomerase is reported that its activity in the tumor and stem cells more than 90%, the plasmid vectors of the invention a variety of tumor therapy and stem cell It can be useful in the differentiation control.