OSTEOGENIC DIFFERENTIATION OF HUMAN MESENCHYMAL STEM CELLS USING HISTONE DEACETYLASE INHIBITORS

摘要

The invention of bone mesenchymal stem cells (MSC) by the histone deacetylase (HDAC) inhibitors relates to a processing method of the differentiation inducing action and HDAC inhibitors . ; According to the present invention , pre-treatment of HDAC inhibitors can be seen that significantly increasing the bone cell differentiation inducing effect on the mesenchymal stem cells . Thus, it is possible by the HDAC inhibitors HDAC inhibitors were prepared on the basis that promote the differentiation of bone marrow cells used for bone regeneration technology development with differentiation inducers .