PNA CHIP FOR GENOTYPING MYCOBACTERIA SPECIES USING PLASTIC SUBSTRATE COATED WITH POLYMER HAVING EPOXY GROUPS AND METHOD FOR GENOTYPING MYCOBACTERIA SPECIES USING THE PNA CHIP

摘要

The invention PNA chip for mycobacteria genotype of probe PNA (peptide nucleic acid) characterized in that the immobilized polymer comprises the DNA sequence of SEQ ID NO: 5 to SEQ ID NO: 28 over the coated plastic substrate is detected with an epoxy group and the using the PNA chip to a method of detecting a genotype of mycobacteria. Using the PNA chip and method according to the invention it is possible to perform high sensitivity and specificity for causative organisms of genotype analysis of mycobacteria in tuberculosis and respiratory diseases in a short period of time, whether the presence of the mycobacterial specimen, if present the mycobacteria are Mycobacterium species and whether it can quickly and accurately determine his specific species. ; Mycobacteria, genotype, a plastic substrate, PNA chip