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PNA chip for genotyping mycobacteria species using plastic substrate coated with polymer having epoxy groups and method for genotyping mycobacteria species using the PNA chip
PNA chip for genotyping mycobacteria species using plastic substrate coated with polymer having epoxy groups and method for genotyping mycobacteria species using the PNA chip
The present invention is an epoxy group to which the polymer-coated plastic substrate over SEQ ID NOS .: 5 to 28 of the DNA sequence to include the probe PNA (peptide nucleic acid) is immobilized characterized in that mycobacterial genotype detected for PNA chip and the using the PNA chip to a method of detecting a genotype of mycobacteria. Using the PNA chip and method according to the invention it is possible to perform high sensitivity and specificity for causative organisms of genotype analysis of mycobacteria in tuberculosis and respiratory diseases in a short period of time, whether the presence of the mycobacterial specimen, if present the mycobacteria are Mycobacterium species and whether it can quickly and accurately determine his specific species. ; Mycobacteria, genotype, a plastic substrate, PNA chip
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机译:本发明是环氧基,其固定了DNA序列的SEQ ID NO:5至28上的聚合物包被的塑料底物,以包括探针PNA(肽核酸),其特征在于检测到的PNA芯片的分枝杆菌基因型和将PNA芯片用于检测分枝杆菌基因型的方法。使用本发明的PNA芯片和方法,可以在短时间内对结核分枝杆菌和呼吸系统疾病中分枝杆菌的基因型分析的致病菌进行高灵敏度和特异性分析,无论是否存在分枝杆菌标本分枝杆菌属于分枝杆菌属,它是否可以快速,准确地确定其具体种类。 ;分枝杆菌,基因型,塑料底物,PNA芯片
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