MAGNETIC FORCE-BASED MICROFLUIDIC CHIP USING MAGNETIC NANOPARTICLES AND MICROBEADS, AND BIOASSAY APPARATUS AND METHOD USING THE SAME

摘要

The present invention relates to a magnetic force-based microfluidic chips and bio-assay device and in vivo analysis method using the same with the magnetic nanoparticles 11 and the microbeads 12, the magnetic nanoparticles (11) coupled by a biomolecular reaction, microbeads 12 and the detection molecule (14) the reactants are under the influence of the magnetic force applied from the path changing unit (5) the magnetic force applying unit (7) in the microfluidic channel of the changes its flow path, the path change or absence the present invention relates to magnetic force-based microfluidic chip and a biometric analysis apparatus and analysis method using the living body comprises a structure that can be found on the path identification unit (6). ; The present invention provides a biomolecule to enable quantitative and highly sensitive analysis by monitoring the path variation of microparticles going by changing the magnetic field in order to know the concentration of a specific detection target biomolecule in the intensity and amount of change in the specific magnetic field, in a single reaction various in enabling the construction of a biomolecule multi-detection system (multiplexed detection system) capable of detecting. ; Magnetic force based biological analysis, magnetic nanoparticle, a microfluidic chip, a multi-detection