PROTEIN HAVING NUCLEUS LOCALIZATION SIGNAL SEQUENCE

摘要

PURPOSE: A protein having a nucleus localization signal sequence is provided. The protein relates to nucleus or nucleolus targeting. CONSTITUTION: The protein has a nucleus localization signal sequence relating to nucleus or nucleolus targeting of Aplysia kurodai, wherein nucleus or nucleolus is encoded by the nucleotide sequence set forth in SEQ ID NO:1, and is present in the site encoded by the 85th to 142th and 355th to 445th nucleotides. The protein has a nucleus localization signal sequence which relates to nucleus or nucleolus targeting of human, wherein nucleus or nucleolus is encoded by the amino acid sequence set forth in SEQ ID NO:5, and is present in the site encoded by the 103th to 119th amino acids. The protein has a nucleus localization signal sequence relating to nucleus or nucleolus of mouse, wherein nucleus or nucleolus is encoded by the nucleotide sequence set forth in SEQ ID NO:6, and is present in the site encoded by the 47th to 107th and 364th to 413th nucleotides. Primers for producing the nucleus localization signal sequence has the nucleotide sequences of SEQ ID NO:9, SEQ ID NO:10, SEQ ID NO:12 or SEQ ID NO:14.