首页> 外国专利> Vector system for construction of recombinant Aujeszky's disease virus gene using thymidine kinase selection

Vector system for construction of recombinant Aujeszky's disease virus gene using thymidine kinase selection

机译:利用胸苷激酶选择技术构建重组奥杰斯基病病毒基因的载体系统

摘要

The present invention thymidine kinase (Thymidine kinase; hereinafter "TK" hereinafter) selection (selection) the use of recombinant virus selection process through domestic separating pigs ohjeseuki disease virus genes of pathogenic and associated with three types of gene UL21, TK and remove the gE gene, and relates to a viral vector system manufactured by inserting instead of the useful gene outside in that area. ; In the present invention, it is possible to create a viral vector system and easily overcome the difficulties of the recombinant virus screening recombinant pig ohjeseuki disease virus by using the prepared above. ; Ohjeseuki pig disease virus, recombinant vector, thymidine kinase, drug selection, TK gene, UL21 gene, gE gene
机译:本发明的胸苷激酶(胸腺嘧啶激酶;以下简称“ TK”)的选择(选择)是利用重组病毒的选择方法,通过分离猪大叶轻病病原体的致病基因和与UL21,TK三类基因相关的基因并去除gE基因,并涉及一种病毒载体系统,该病毒载体系统是通过在该区域之外而不是在该区域外部插入有用基因而制造的。 ;在本发明中,可以通过使用以上制备的方法来创建病毒载体系统并容易克服重组病毒筛选重组猪大叶病病毒的困难。 ;大j猪病病毒,重组载体,胸苷激酶,药物选择,TK基因,UL21基因,gE基因

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