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Method for the selective removal of proteins from biological samples using chemicals

机译:使用化学物质从生物样品中选择性去除蛋白质的方法

摘要

This invention relates to compounds of formula (I) in a biological sample containing protein: ; [Formula I] ; [wherein, R 1 , R 2 , and R 3 are each independently a hydrogen atom or a substituted or unsubstituted an alkyl group having 1 to 6, a is an integer from 1 to 6 (provided that the amine contains two or more alkyl groups) and adding a nucleating protein substance (nucleating agent); Processing the mixture with a hydrophobic surface material; And a method of removing nucleic acid in the protein, while maintaining the biological sample comprising the step of separating the sample from the hydrophobic surface of the protein material is combined. According to the present invention a protein from a biological sample containing protein is efficiently removed, and the nucleic acid can be selectively removed by having the protein present in the sample.
机译:本发明涉及含有蛋白质的生物样品中的式(Ⅰ)化合物: [公式I]; [其中,R 1 ,R 2 和R 3 各自独立地是氢原子或具有1至1的烷基的取代或未取代的烷基。在图6中,a是1〜6的整数(假设胺含有两个以上的烷基),并添加有核蛋白物质(成核剂)。用疏水表面材料处理混合物;并且,结合了在保持生物样品的同时去除蛋白质中的核酸的方法,该方法包括将样品与蛋白质材料的疏水性表面分离的步骤。根据本发明,可以有效地从含有蛋白质的生物样品中去除蛋白质,并且可以通过使蛋白质存在于样品中来选择性地去除核酸。

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