MIXED VACCINE BASED ON ANTIGENS OF MICROORGANISM MORAXELLA BOVIS AND HERPES VIRUS TYPE I FOR SPECIFIC PROPHYLAXIS OF INFECTIOUS KERATOCONJUNCTIVITIS IN CATTLE

摘要

FIELD: veterinary microbiology, virology, biotechnology.;SUBSTANCE: invention proposes vaccine that comprises as antigens the following components, vol. %: inactivated suspension of cells of hemolytic strains of microorganism M. bovis with the total concentration 100-120 billion cells in 1 cm³: strain M. bovis "G97-VNIVI", 4.0-5.0; strain M. bovis "SHZ-01", 4.0-5.0; inactivated cultural suspension of the strain Herpesvirus bovis type I "TKA-VIEV-V2" with infectious titer 10^7.0 - 10^7.5 TCD₅₀/ml, 78.0-83.0; 6% solution of aluminum hydroxide gel, the balance. Vaccine enhances accumulation of specific protective antibodies in serum blood of vaccinated animals and provides the development of immunity against infectious keratoconjunctivitis that is retained for one year.;EFFECT: enhanced effectiveness and valuable properties of vaccine.;4 tbl, 6 ex