METHOD FOR DIFFERENTIAL DIAGNOSTICS OF LYMPHADENOPATHIES OF DIFFERENT GENESIS IN CHILDREN

摘要

FIELD: medicine, oncology.;SUBSTANCE: in plasma of peripheral blood in children one should detect cathepsin D activity and antiproteolytic activity and calculate coefficient of their ratio. At obtaining the value of coefficient being equal 10.5 ± 2 one should detect lymphadenopathy of benign genesis in a child to choose a waiting-type tactics at prescribing antiphlogistic therapy. At coefficient value ranged 30-100 on should detect malignant lymphoproliferative process in a child to immediately fulfill an excision biopsy of a lymph node along histological studying and at proving the diagnosis special therapy should be indicated. Application of the present method enables to conduct additional objective differential-diagnostic test under disputable cases at the stage being before carrying out histological analysis of lymph nodes and prescribe necessary therapy for every concrete case in due time.;EFFECT: higher accuracy of differential diagnostics.;3 ex, 1 tbl