ANTIBACTERIAL AGENT AND PHARMACEUTICAL COMPOSITION COMPRISING EFFECTIVE AMOUNT OF ANTIBACTERIAL AGENT

摘要

FIELD: medicine, biotechnology.;SUBSTANCE: invention relates to preparing biologically active substances from human and animal tissues. Invention proposes an antibacterial agent from pig and cattle platelets of molecular mass 0.5-15 kDa. Agent is prepared by freezing and defrosting platelet mass at temperature (-15)-(-20)°C for 24 h, centrifugation at 1000g, filtration of supernatant through dialysis membranes 15000 and 500 and elution of component comprising peptides by acetonitrile linear gradient from Sephadex G-50. Invention provides the synergetic antibacterial effect of peptides as component of the agent.;EFFECT: improved preparing method, valuable properties of agent.;8 cl, 6 tbl, 7 ex