2-ETHYL-6-METHYL-3-OXYPYRODINE SALTS WITH ORGANIC CARBOXYLIC ACIDS POSSESSING ANXIOLYTIC, ANTIDEPRESSIVE, ANTIHYPOXIC, ANTI-AMNESTIC AND ANTI-OXIDATIVE ACTIVITY AND METHOD FOR THEIR PREPARING

摘要

FIELD: organic chemistry, medicine, pharmacy.;SUBSTANCE: invention relates to pharmaceutically acceptable 2-ethyl-6-methyl-3-oxypyridine salts with organic carboxylic acids of the general formula: (1-V1): wherein R means -CH₂OH (I); R means -CH₂-COOH (II); R means -(CH₂)₃-COOH (III); R means -(CH₂)₄-COOH (IV); R means -CH(OH)-CH(OH)-COOH (V); R means -CH(NH₂)-CH₂-COOH (VI) possessing with anxiolytic, antidepressive, antihypoxic, anti-amnestic and anti-oxidative activity and showing decreased toxicity. Also, invention relates to a method for preparing salts and pharmaceutical composition.;EFFECT: improved preparing method, valuable medicinal properties of compounds and pharmaceutical composition.;3 cl, 10 tbl, 10 ex