首页>
外国专利>
A method of increasing the bioavailability of alendronate or another bisphosphonate by administering a pre-dose of a vitamin D derivative
A method of increasing the bioavailability of alendronate or another bisphosphonate by administering a pre-dose of a vitamin D derivative
展开▼
机译:一种通过服用维生素D衍生物的预给药来提高阿仑膦酸盐或另一种双膦酸盐的生物利用度的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention provides a method of increasing the bioavailability of a bis-phosphonate comprising administering an effective predose of a vitamin D derivative, such as alphacalcidol or calcitriol, and after a time interval, administering a therapeutic dose of bis-phosphonate, such as alendronate. The present invention also relates to the use of vitamin D derivatives and bisphosphonates for the manufacture of medicaments for treating osteoporosis, metastatic bone disease, and Paget's disease.
展开▼