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NEW ANALOGY OF 16-HYDROXYEICOSATETRAENIC acid

机译:16-羟基己酸酯酸的新类似物

摘要

The present invention includes 16-HETE analogs which are agonists and antagonists of 16-HETE. The compositions may be formulated in pharmaceutically acceptable formulations. The invention also includes methods and products for inhibiting neutrophil adhesion and neutrophil aggregation using the 16-HETE agonists. One method of the invention involves the administration of a 16-HETE agonist in combination with a thrombolytic agent to a patient suffering from thromboembolic stroke.
机译:本发明包括16-HETE类似物,其是16-HETE的激动剂和拮抗剂。可以将组合物配制成药学上可接受的制剂。本发明还包括使用16-HETE激动剂抑制嗜中性粒细胞粘附和嗜中性粒细胞聚集的方法和产品。本发明的一种方法涉及将16-HETE激动剂与血栓溶解剂组合给予患有血栓栓塞性中风的患者。

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