首页> 外国专利> BIPHENYL DERIVATIVE HAVING beta2 ADRENERGIC RECEPTOR ANTAGONIST ACTIVITY AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY

BIPHENYL DERIVATIVE HAVING beta2 ADRENERGIC RECEPTOR ANTAGONIST ACTIVITY AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY

机译:具有β2肾上腺素受体拮抗剂活性和肌肉受体拮抗剂活性的联苯衍生物

摘要

PPROBLEM TO BE SOLVED: To provide a new biphenyl derivatives possessing both 2 adrenergic receptor agonist activity and muscarinic receptor antagonist activity and useful for treating pulmonary disorders such as chronic obstructive pulmonary disease and asthma. PSOLUTION: The compounds of formula I, or a pharmaceutically acceptable salt, solvate or stereoisomer thereof is provided, wherein RSP1/SP, RSP2/SP, RSP3/SP, RSP4/SP, RSP5/SP, RSP6/SP, RSP7/SP, W, a, b and c are as defined in the specification. PCOPYRIGHT: (C)2007,JPO&INPIT
机译:<待解决的问题:提供一种兼具2肾上腺素能受体激动剂活性和毒蕈碱受体拮抗剂活性的新型联苯衍生物,可用于治疗诸如慢性阻塞性肺疾病和哮喘的肺部疾病。

溶液:提供了式I化合物或其药学上可接受的盐,溶剂化物或立体异构体,其中R 1 ,R 2 ,R 3 ,R 4 ,R 5 ,R 6 ,R 7 ,W,a,b和c如说明书中所定义。

版权:(C)2007,日本特许厅&INPIT

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