SPECIFIC IMMUNOTHERAPY OF CANCER USING LIVE RECOMBINANT BACTERIAL VACCINE VECTOR

摘要

PPROBLEM TO BE SOLVED: To provide a vaccine for treating cancers, containing recombinant Listeriamonocytogenes expressing a tumor-specific antigen or a fragment thereof. PSOLUTION: The vaccine contains recombinant Listeria monocytogenes expressing Listeriolysin O (LLO) fusion protein to a tumor-specific antigen or a fragment thereof for suppressing tumor formation in a host. PCOPYRIGHT: (C)2008,JPO&INPIT