METHOD FOR PREPARING POROUS POLYMER SCAFFOLD FOR TISSUE ENGINEERING USING GEL SPINNING MOLDING TECHNIQUE

摘要

PROBLEM TO BE SOLVED: To provide a simple method for preparing a porous polymer scaffold suitable for tissue engineering, which is uniform pore size, excellent in the interconnectivity between the pores, high in cell seeding and proliferation efficiencies, and excellent in mechanical strength.;SOLUTION: The porous polymer scaffold is prepared by dissolving polymer in an organic solvent, radiating it to a non-solvent which is stirred with a rotating template shaft, and performing molding while winding polymer fibers in a gel state to be phase-separated around the rotating mold shaft. The interconnectivity between the pores is excellent and the mechanical strength and cell seeding and proliferation efficiencies are high in the manufacturing method, so that the porous polymer scaffold suitable for tissue engineering is obtained.;COPYRIGHT: (C)2007,JPO&INPIT