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Methods of using immunomodulatory compounds for treating and managing skin diseases or disorders and compositions containing the same

机译:使用免疫调节化合物治疗和控制皮肤疾病或病症的方法以及包含该化合物的组合物

摘要

The invention relates to methods of treating, preventing, correcting and/or managing skin diseases or disorders characterized by overgrowths of the epidermis, keratoses, scleroderma, cutaneous vasculitis, acne or wrinkles are disclosed. Specific embodiments encompass the administration of an immunomodulatory compound, or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer, clathrate, or prodrug thereof, alone or in combination with a second active agent. Specific second active ingredients are capable of affecting or inhibiting cell growth or proliferation, removing or improving acne scars, or reducing or correcting wrinkle lines. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed.
机译:本发明涉及治疗,预防,纠正和/或控制以表皮,角质层蛋白,硬皮病,皮肤血管炎,痤疮或皱纹过度生长为特征的皮肤疾病或病症的方法。具体实施方案包括单独或与第二活性剂组合施用免疫调节化合物或其药学上可接受的盐,溶剂化物,水合物,立体异构体,包合物或前药。特定的第二活性成分能够影响或抑制细胞生长或增殖,去除或改善痤疮疤痕,或减少或纠正皱纹。还公开了适用于本发明方法的药物组合物,单一单位剂型和试剂盒。

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