METHOD FOR JUDGING ONSET OF PULMONARY ALVEOLAR MICROLITHIASIS

摘要

PPROBLEM TO BE SOLVED: To provide a method for judging the presence of known alteration in the human SLC34A2 gene of an examinee to cause the onset of pulmonary alveolar microlithiasis, provide a method for judging the onset risk of an examinee before the onset of pulmonary alveolar microlithiasis and establish the cause of the disease for an examinee suspected to be affected by pulmonary alveolar microlithiasis and provide an effective treatment to a patient of pulmonary alveolar microlithiasis. PSOLUTION: The invention provides a method for extracting a nucleic acid or a protein from an examinee and detecting a known alteration in the human SLC34A2 gene and human type IIb sodium-phosphate cotransporter protein or an alteration from a wild-type base sequence or an amino acid alteration from a wile-type amino acid sequence, and provides a mutant primer and a clamp primer therefor. The invention further provides a method for the treatment of pulmonary alveolar microlithiasis using a corrected gene based on human SLC34A2 gene. PCOPYRIGHT: (C)2007,JPO&INPIT