TECHNIQUE FOR SYNTHESIS INTEGRITY EVALUATION UTILIZING CYCLE FIDELITY PROBE

摘要

PROBLEM TO BE SOLVED: To provide a technique for designing a polymer probe to verify the integrity of the probe synthesis.;SOLUTION: Multiple probes with identical sequences are designed to form the probes containing at least one different monomer addition cycle. The variation (e.g., error) in probe synthesis is identified based on the probe affinity to a control target.;COPYRIGHT: (C)2007,JPO&INPIT