REDUCTION OF INFARCT VOLUME USING CITICOLINE

摘要

PROBLEM TO BE SOLVED: To provide combination medicament for treatment of a subject who experienced an ischemic event.;SOLUTION: A method reduces the extent of infarction, particularly cerebral infarction subsequent to cerebral ischemia, by the administration of citicoline shortly after an ischemic episode and continuing daily treatment for up to about 30 days, preferably for at least about 6 weeks. The method is useful in the treatments of stroke and severe head trauma patients and maximizes the chances for a full or substantially full recovery of the patient. Combination treatment regimens are also disclosed along with compositions for use therewith.;COPYRIGHT: (C)2007,JPO&INPIT