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Corneal epithelial disorder model animal, drug evaluation method using the model animal, and drug selected using the evaluation method
Corneal epithelial disorder model animal, drug evaluation method using the model animal, and drug selected using the evaluation method
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机译:角膜上皮疾病模型动物,使用该模型动物的药物评估方法以及使用该评估方法选择的药物
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摘要
An excellent model animal having a corneal epithelial damage, an excellent method of evaluating a medicine using the model animal, and an excellent medicine selected by the evaluation method are provided. A model animal having a corneal epithelial damage, characterized in that the corneal epithelial damage is caused by contacting an ocular cornea of the animal with a water-absorbing material and thereby generating the difference in osmotic pressure between the inside and outside of corneal epithelium cells; a method of evaluating a medicine characterized by using the model animal; and a medicine selected by the evaluation method.
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