SOLID-LIQUID MIXED TYPE TWO-COMPONENT SYSTEM IN VIVO DECOMPOSING AND ABSORBING ADHESIVE MEDICAL MATERIAL

摘要

PROBLEM TO BE SOLVED: To provide an in vivo decomposing and absorbing adhesive medical material to be strongly adhered in a short time without using dimethylsulfoxide which is an organic solvent as a solvent.;SOLUTION: In the solid-liquid mixed type two-component system in vivo decomposing and absorbing adhesive medical material, biodegradable polymer dissolved in the solvent composed of distilled water, an aqueous solution containing metal ions to electrostatically interact with the biodegradable polymer and interact by a chelate effect or a buffer solution is used as an adhesive component, and an organic acid derivative in a powder shape obtained by modifying two carboxyl groups of dicarboxylic acid or two or three carboxyl groups of tricarboxylic acid by an electron withdrawing group is used as a hardening component.;COPYRIGHT: (C)2007,JPO&INPIT