The optical fiber array biochip which is based on the spectrum change rule of white optical reflection interference

摘要

As for this device, the special organism of a certain kind (or chemistry) the optical fiber array biochip which applies, the spectrum change rule of white optical reflection interference in order to detect the existence and change of the substance is disclosed. The said tip/chip has used the optical fiber, as the biosensor in order to be able to become perception standard of the thin film reflected interference measurement equipment, the optical fiber and the suffering inspection substance above it differs more, being something which applies the material to the end of the optical fiber, among these at least more the suffering inspection target organism (or chemistry) the molecule it is the adsorption possible complimentary material. The suffering inspection child changes the surface of the complimentary material or after being adsorbed inside, spectrum distribution of reflected interference light. Although deviation of this kind of spectrum line, in other words density of the sample molecule, quantitative or analyzes the change of rate of adsorption, and geometric size qualitatively, it is used. Arranging the plural optical fibers into linear array or surface condition array, as it forms the biochip, N: The optical fiber coupler of 1 together, parallelism detection of the plural signs of the single reagent of the biochemical substance by one detection device or the plural signs of the plural reagents becomes possible.