Granular ones where the sustained-release granular formulation and

摘要

The present invention is a wet granulation of a water suspension containing a powdery substance and an average particle size of 50. Mu. M or less and a plasticizer containing a plasticizer, and the resulting granular material is lower than the minimum coating temperature or glass transition temperature of the mixture of the polymer and the plasticizer The present invention relates to a sustained release granular formulation obtained by treating at a time and its manufacturing method. According to the present invention, it is possible to easily manufacture a granular pharmaceutical having excellent release releasing property and high safety to the human body by a simple method.