Phosphinoselenoic amide, Serenorin acid amide, and methods for their preparation Serenorin acid chloride

摘要

Phosphinoselenoic amides of the present invention has a structure represented by the following general formula (1). Serenorin acid amide has a structure represented by the following general formula (4). Having a structure represented by the following general formula (7), (R) form or Serenorin acid chloride is (S) body. In the following formulas, Ph represents phenyl group, R ² and R ¹ represents an alkyl group, R ³ represents a hydrogen atom or an alkyl group, one of an alkyl group at least a chiral selected from R ² and R ³ . R ⁴ and R ⁸ represents a silyl group hydrogen atom, a halogen atom, an alkyl group, an aryl group, an alkoxy group, R ⁵ is an alkyl group or piperidyl -NR ⁶ R ^7. R ⁶ represents a hydrogen atom or an alkyl group, R ⁷ is an alkyl group. [Formula 1] [2] of [3] of