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Near-infrared fluorescent tracer and fluorescence imaging method

机译:近红外荧光示踪剂及荧光成像方法

摘要

PROBLEM TO BE SOLVED: To provide a near-infrared fluorescent tracer and a fluorescent imaging. SOLUTION: This near-infrared fluorescent tracer comprises a complex which contains at least near-infrared fluorescent-coloring and a substance containing a fat-soluble component and additionally possesses a recognition site for test substance. The infrared fluorescent-coloring matter is an indocyanine-based coloring matter and the substance containing a fat-soluble component is the near-infrared fluorescent tracer consisting of a lipoprotein with a high density. The recognition site for test substance is to be an antibody. The external imaging method is provided by introducing the near-infrared fluorescent tracer into the body system, irradiating the body system with an exciting light and then detecting the near-infrared fluorescence from the tracer.
机译:要解决的问题:提供近红外荧光示踪剂和荧光成像。解决方案:该近红外荧光示踪剂包括一种复合物,该复合物至少包含近红外荧光色和一种物质,该物质含有一种脂溶性成分,另外还具有用于测试物质的识别位点。红外荧光色素是基于吲哚菁的色素,并且包含脂溶性成分的物质是由高密度脂蛋白构成的近红外荧光示踪剂。测试物质的识别位点应为抗体。通过将近红外荧光示踪剂引入身体系统,用激发光照射身体系统,然后检测来自示踪剂的近红外荧光来提供外部成像方法。

著录项

  • 公开/公告号JP3896176B2

    专利类型

  • 公开/公告日2007-03-22

    原文格式PDF

  • 申请/专利权人 浜松ホトニクス株式会社;

    申请/专利号JP19960149959

  • 发明设计人 治部 雅貴;酒谷 薫;

    申请日1996-05-21

  • 分类号A61K49/00;A61B10/00;

  • 国家 JP

  • 入库时间 2022-08-21 21:08:25

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