Pharmaceutical preparations for treating hypertension and dyslipidemia with Allium ursinum and Allium sativum

摘要

Wild Garlic (Bear's or Forest Garlic, Allium ursinum) can be combined with cultivated high-allicin garlic (Allium sativum) and extracts of the same to take advantage of the previously unknown synergism of preparations made from these two garlic species. There is a substantial cost savings over the use of pure, Wild Garlic and an elimination of the side effects found with the chronic ingestion of high levels of cultivated allicin-rich garlic (Allium sativum). The resulting combination has demonstrated benefits with regard to blood lipids regulation in individuals in need thereof that are two or more times that expected from the use of either garlic species taken singularly. Blood pressure regulating benefits are maintained or improved, the odor-causing potential of high-allicin garlic is reduced, and significant improvements are found in the areas of total, LDL, and VLDL cholesterol and triglycerides, benefits far beyond the merely additive. HDL cholesterol levels also are improved. It is to be expected that these benefits, in addition, can be extended through the concurrent intake of folic acid, red yeast rice extracts and other compounds proposed for improving cardiovascular health. Still further, a variety of defined delivery approaches, including, but not limited to controlled releases, especially those including mucoadhesive, can be utilized to improve the effects taught herein.