Use of proteinaceous molecules in methods for molecular computing

摘要

The present invention provides proteinaceous molecules to encode solutions to computational problems. In one aspect, a proteinaceous molecule is used as a representation of a combination of values for variables of a computational problem. In a second aspect, a library of proteinaceous molecules representing essentially all relevant solutions to at least one computational problem are used. The invention further provides a nucleic acid library encoding a library of proteinaceous molecules according to the invention. In another aspect, the invention includes a method for detecting a proteinaceous molecule representing a combination of values for variables of a computational problem comprising contacting a library of proteinaceous molecules of the invention, with a set of binding molecules designed for binding to proteinaceous molecules representing solutions. The invention also provides an apparatus for providing a solution to a computational problem comprising a library of the invention, and a system for detection of a solution.