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Radionuclide labeling of vitamin B12 and coenzymes thereof
Radionuclide labeling of vitamin B12 and coenzymes thereof
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机译：维生素B12及其辅酶的放射性核素标记
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摘要
A compound useful for in vivo imaging of organs and tumors is provided of formula: wherein is a cobalamin, is derived from a corrin carboxylic acid group of said cobalamin, Y is a linking group and X is a chelating group, optionally comprising a detectable radionuclide or a paramagnetic metal ion, and n is 1-3.
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机译：提供了可用于体内器官和肿瘤成像的化合物，其分子式为： <图像alt =“嵌入式图像” file =“ US20070110667A1-20070517-C00001.GIF” he =“ 10.84mm” imgContent =“ chem” imgFormat =“ GIF” wi =“ 24.89mm“ /> 其中 <图像alt =“嵌入式图像” file =“ US20070110667A1-20070517-C00002.GIF” he =“ 10.92mm” imgContent =“ chem” imgFormat =“ GIF” wi =“ 4.66mm“ /> 是钴胺素 <图像alt =“嵌入式图像” file =“ US20070110667A1-20070517-C00003.GIF” he =“ 7.62mm” imgContent =“ chem” imgFormat =“ GIF” wi =“ 1.86mm“ /> R 2是衍生自所述钴胺素的Corrin羧酸基团，Y是连接基团，X是螯合基团，任选地包含可检测的放射性核素或顺磁性金属离子，并且n是1-3。
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