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Controlling dendritic cell maturation state in the lymphoid tissue equivalent of an artificial immune system

机译:控制相当于人工免疫系统的淋巴组织中的树突状细胞成熟状态

摘要

The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the normal tissues that interact with vaccines in mammals. The artificial immune system can be used to test the efficacy of vaccine candidates in vitro and thus, is useful to accelerate vaccine development and testing drug and chemical interactions with the immune system.
机译:本发明涉及构建整合的人工免疫系统的方法,该系统包括合适的体外细胞和组织构建体或其等同物,以模拟与哺乳动物中与疫苗相互作用的正常组织。人工免疫系统可用于体外测试候选疫苗的功效,因此可用于加速疫苗开发以及测试与免疫系统的药物和化学相互作用。

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