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Nitroglycerin therapy for those unable to metabolize nitroglycerin

机译:硝酸甘油疗法用于那些无法代谢硝酸甘油的人

摘要

Those in need of nitroglycerin (GTN) therapy who have polymorphism in the mtALDH gene, e.g., those of Asian descent for whom this polymorphism is common, and/or who are being treated with or ingesting or exposed to mtALDH inhibitor are treated with GTN in combination with agent which converts GTN to product which is metabolized without mtALDH activity, e.g., N-acetylcysteine.
机译:需要mtALDH基因多态性的需要硝酸甘油(GTN)治疗的患者,例如,具有该多态性的亚洲人后裔,和/或接受mtALDH抑制剂治疗或摄入或暴露于其的人,应在GALD中进行治疗。与将GTN转化为可被代谢而没有mtALDH活性的产物(例如N-乙酰半胱氨酸)结合使用。

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