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Nucleotide array containing polynucleotide probes complementary to, or fragments of, cynomolgus monkey genes and the use thereof

机译:包含与食蟹猴基因互补或片段的多核苷酸探针的核苷酸阵列及其用途

摘要

This invention relates to a nucleotide array containing polynucleotide probes complementary to, or fragments of, Cynomolgus monkey genes, and the use of such a nucleotide array to characterize the biological effects, including the actions, targets, and toxicities, of therapeutic agents in primates, e.g., a human, a Cynomolgus monkey, or a Rhesus monkey, in particular a nucleotide array to be used in identifying the toxicities of therapeutic agents administered to a non-human primate, e.g., a Cynomolgus monkey or a Rhesus monkey.
机译:本发明涉及一种含有与食蟹猴基因互补或片段的多核苷酸探针的核苷酸阵列,以及这种核苷酸阵列在灵长类动物中表征治疗剂的生物学作用,包括作用,靶标和毒性的用途,例如,人,食蟹猴或恒河猴,特别是用于鉴定施用于非人灵长类动物例如食蟹猴或恒河猴的治疗剂的毒性的核苷酸阵列。

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