A method of treating lipomatous tumors in mammals such as humans or companion animals is described. The treatment of lipomatous tumors use antibodies derived from adipose tissue of a mammal donor. The methods of the present invention are effective against both benign and malignant lipomatous tumors. The antibodies of the present invention are used to decrease the size of lipomatous tumors, prevent the regrowth of removed tumors, and inhibit the proliferation of lipomatous cells.
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