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Methods of administering/dosing CD2 antagonists for the prevention and treatment of autoimmune disorders or inflammatory disorders

机译:预防和治疗自身免疫性疾病或炎性疾病的CD2拮抗剂给药/给药方法

摘要

The present invention provides compositions for the prevention or treatment of an autoimmune disorder or an inflammatory disorder in a subject comprising one or more CD2 antagonists. In particular, the invention provides methods for preventing or treating an autoimmune disorder or an inflammatory disorder in a subject comprising administering one or more CD2 binding molecules to said subject. The present invention provides doses of CD2 binding molecules and methods of administration that result in improved efficacy, while avoiding or reducing the adverse or unwanted side effects associated with the administration of an agent that induces the depletion of peripheral blood lymphocytes.
机译:本发明提供了用于预防或治疗受试者的自身免疫疾病或炎性疾病的组合物,其包含一种或多种CD2拮抗剂。特别地,本发明提供了用于预防或治疗受试者的自身免疫疾病或炎性疾病的方法,其包括向所述受试者施用一种或多种CD2结合分子。本发明提供了剂量的CD2结合分子和给药方法,其导致功效提高,同时避免或减少了与引起外周血淋巴细胞消耗的试剂的给药相关的不利或不希望的副作用。

著录项

  • 公开/公告号US2007025990A1

    专利类型

  • 公开/公告日2007-02-01

    原文格式PDF

  • 申请/专利权人 CHRISTINE DINGIVAN;

    申请/专利号US20060541237

  • 发明设计人 CHRISTINE DINGIVAN;

    申请日2006-09-29

  • 分类号A61K39/395;

  • 国家 US

  • 入库时间 2022-08-21 21:03:06

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