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Rapid Isolation of Osteoinductive Protein Mixtures from Mammalian Bone Tissue
Rapid Isolation of Osteoinductive Protein Mixtures from Mammalian Bone Tissue
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机译:从哺乳动物骨组织中快速分离成骨蛋白混合物
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摘要
A method for purifying bone-derived osteoinductive proteins including a demineralization process, a protein extraction process, a high molecular weight ultrafiltration process, a low molecular weight ultrafiltration process, and a recovery process. The high and low ultrafiltration processes preferably select proteins having a nominal molecular weight between approximately 8 kilodaltons and approximately 100 kilodaltons. Processes of the present invention may be used to recover osteoinductive proteins from bone demineralization waste streams.
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