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Methods and compositions for identifying therapeutic compounds with GS-9005 ester hydrolase B
Methods and compositions for identifying therapeutic compounds with GS-9005 ester hydrolase B
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机译:GS-9005酯水解酶B鉴定治疗性化合物的方法和组合物
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摘要
By the present invention, enzymes responsible for prodrug activation are identified and utilized for the identification of candidate compounds as prodrugs. The present invention includes methods for identifying a candidate compound as a suitable prodrug as well as methods of screening candidate compounds for suitability as therapeutic agents.
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