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EBV-infected stomach cancer cell line

机译:EBV感染的胃癌细胞系

摘要

An EBV strain infecting epithelial cells and a stomach cancer cell line cancerated by EBV are established to clarify the mechanism of canceration of epithelial cells into stomach cancer by EBV and to develop a chemotherapeutic agent for stomach cancer cancerated by EBV. Further, a stomach cancer cell line stably producing EBV-related antigens is established to develop a diagnostic drug for stomach cancer cancerated by EBV. According to the present invention, GTC-4 cell line was established through culture of stomach cancer tissues. GTC-4 produced the EBV strain infecting epithelial cells and simultaneously produced EBV-related antigens stably in the supernatant.
机译:建立了一种感染上皮细胞的EBV菌株和被EBV致癌的胃癌细胞系,以阐明EBV将上皮细胞癌化为胃癌的机理,并开发出用于治疗被EBV致癌的胃癌的化学治疗剂。此外,建立稳定产生EBV相关抗原的胃癌细胞系,以开发用于由EBV致癌的胃癌的诊断药物。根据本发明,通过培养胃癌组织来建立GTC-4细胞系。 GTC-4产生了感染上皮细胞的EBV菌株,同时在上清液中稳定地产生了EBV相关抗原。

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