The present invention relates to the cloning of novel cDNA sequences encoding the α4 and δ receptor subunits of the human GABA A receptor; to stably co-transfected eukaryotic cell lines capable of expressing a human GABAA receptor, which receptor comprises at least one of the novel α4 and δ receptor subunits; and to the use of such cell lines in screening for and designing medicaments which act upon the human GAGAA receptor.
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机译:本发明涉及编码人GABA A Sub>受体的α 4 Sub>和δ受体亚基的新cDNA序列的克隆。稳定共转染能表达人GABA A Sub>受体的真核细胞系,该受体包含至少一个新的α 4 Sub>和δ受体亚基;以及在筛选和设计对人GAGA A Sub>受体起作用的药物中使用此类细胞系。
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