Crystalline form of metilamida acid 5 - (1S) - 2 - (2S) - 2 - methyl - 4 - Benzyl - piperazin-1-yl - 1 - methyl - 2 - oxo - ethoxy - 4 - 2 - methoxy - pyridin - carboxylic acid, a process for their preparation, Pharmaceutical compositions to understand and use in Medicine

摘要

Crystalline form of metilamida acid 5 - [(1S) - 2 - [(2R) - 2 - methyl - 4 - Benzoyl - piperazin-1-yl] - 1 - methyl - 2 - oxo - ethoxy - 4 - 2 - methoxy - pyridin acid, processes for the preparation thereof, compositions containing the Crystalline form, and uses the Crystalline form in Medicine The Treatment of AIDS.The metilamida acid 5 - [(1S) - 2 - [(2R) - 2 - methyl - 4 - Benzoyl - piperazin-1-yl] - 1 - methyl - 2 - oxo - ethoxy - 4 - 2 - methoxy - pyridin acid is particularly suitable as a drug substance and Inhibits The Interaction of gp 120 with CD4 and is Therefore useful in the treatment of a retroviral infection on HIV Within genu00e9ticametne with HIV or AIDS.Claim 1: a Crystalline form of metilamida acid 5 - [(1S) - 2 - [(2R) - 2 - methyl - 4 - Benzoyl - piperazin-1-yl] - 1 - methyl - 2 - oxo - ethoxy - 4 - carboxylic acid - 2 - methoxy - pyridin that presents the following characteristic Peaks x-ray Powder diffraction Radiation (when measured using cukalfa longit You Wave = 15406): 20 + / - 0.1 (10.8%); 9; 13; 17.9 15.1; 16.2;.Claim 1: a procedure for the preparation of Crystalline form according to any one of claims 1 to 5 comprising the compound of Formula 1 crystallize