methods and compositions for treating t-cell mediated autoimmune / inflammatory disorders and diseases in subjects having a glucocorticoid regulatory deficiency

摘要

"METHODS AND COMPOSITIONS FOR TREATMENT TREATMENT AND T-CELL MEDIATED AUTO-IMMUNE / INFLAMMATORY DISEASES IN INDIVIDUALS HAVING GLUCOCORTICIDE REGULATION DEFICIENCY". The present invention relates to a method for preventing or treating a T-cell mediated inflammatory / autoimmune disease or disorder in an individual having a glucocorticoid regulatory deficiency, wherein the method comprises administering to an individual in need of such a disorder. treatment a cyclooxygenase-2 inhibitor. The Cox-2 inhibitor may be administered in combination with a glucocorticoid. The Cox-2 inhibitor may be a selective Cox-2 inhibitor. Compositions, pharmaceutical compositions and kits are provided for carrying out the method.