biomarkers for the efficacy of parathyroid hormone and calcitonin treatment

摘要

"BIOMARKERS FOR THE EFFICACY OF PARATHROID HORMONE AND CALCITONINE TREATMENT". The present invention relates to the analysis of the multiorgan genetic profile of the results of an individual administration of salmon calcitonin or a parathyroid hormone analogue that provides biomarkers of the efficacy of calcitonin treatment and the effectiveness of hormone treatment. parathyroid or parathyroid hormone analog. Among the biomarkers are gene expression profiles for Y-box binding protein, BMP-S ~, FGF-S ~, IGF-S ~, VEGF, Î ± -2-HS glycoprotein (AHSG), OSF, receptors (steroid / thyroid family) and others. The results corroborate the anabolic effect of salmon calcitonin on bone metabolism.