n- (4-carbamimidoylbenzyl) -2-alkoxy-2-heterocyclylacet amides as inhibitors of the formation of factor-induced xa, ixa, and thrombin coagulation factors

摘要

"N- (4-CARBAMIMIDOYLBENZYL) -2-ALCoxy-2-HETEROCICLILACE TAMIDES AS INHIBITORS OF THE FORMATION OF XA, IXA AND THROMBIN-INDUCED FACTOR FACTORS". The present invention relates to novel heterocyclyl-substituted mandelic acid-derived groups of formula (I), wherein from R 1 to R 6 and A are as defined in the description and claims, as well as their physiologically salts thereof. acceptable. These compounds inhibit the formation of Vila factor and tissue factor-induced coagulation factors Xa, IXa and thrombin and can be used as medicines.