oncolytic adenovirus recombinant construct specifically expressing a gm-csf immunomodulatory factor in tumor cells and their uses

摘要

CONSTRUCTION OF ONCOLYTIC ADENOVIRUS RECOMBINANT SPECIFICALLY EXPRESSING AN IMMUNOMODULATORY FACTOR GM-CSF IN TUMOR CELLS AND THEIR USES. The present invention relates to tumor gene therapy, specifically, the therapy relates to the construction of the recombined oncolytic adenovirus, which specifically expresses a GM-CSF immunomodulatory factor in tumor cells and their uses.